First and foremost, please be sure to research and buy the necessary adapters for using electricity on your trip. Depending on the duration of your stay, you will be charging your device as often if not more than you would at home (depending on how active you intend to be while abroad), so making sure you can use the outlets in that country properly before you change your device. Some countries have outlets that look exactly like outlets in the U.S. but deliver a higher electrical output that could potentially overload your POC, so be careful.
While looking to fly to other countries, be sure to research all potential air-carriers and the costs associated with them. Some international airlines offer therapeutic medical oxygen on their flights—some for free and others for a fee, so do your homework before committing to a flight with any international airline.
International airlines also have different rules and regulations regarding traveling with POCs, so be in contact with your airline of choice on their guidelines and procedures before you embark on your journey.